Ectoine interaction with DNA: influence on ultraviolet radiation damage

Ultraviolet Radiation Damage in DNA

Introduction The evolution of most forms of life has occurred in an environment exposed to the ultraviolet (UV) and visible radiation emanating from the sun. When molecules in living cells absorb photons in this region of the electromagnetic spectrum they are promoted to excited electronic states and this process can have profound biological consequences. In general, visible wavelengths (400-78...

Radiation track and DNA damage

Molecular Mechanisms of Ultraviolet Radiation-Induced DNA Damage and Repair

DNA is one of the prime molecules, and its stability is of utmost importance for proper functioning and existence of all living systems. Genotoxic chemicals and radiations exert adverse effects on genome stability. Ultraviolet radiation (UVR) (mainly UV-B: 280-315 nm) is one of the powerful agents that can alter the normal state of life by inducing a variety of mutagenic and cytotoxic DNA lesio...

Repair of DNA Damage lnduced by Ultraviolet Radiation

Studies documenting the depletion of the ozone layer and the resulting increases in UV-B radiation (280-320 nm) at the Earth's surface have served to focus attention on the biological effects of UV light. One obvious target for UVB-induced damage is DNA. Although a11 biological tissues are rich in UV-absorbing agents (largely nucleic acids and proteins) and plants produce additional UV-absorbin...

Repair of DNA damage induced by ultraviolet radiation.

Studies documenting the depletion of the ozone layer and the resulting increases in UV-B radiation (280-320 nm) at the Earth's surface have served to focus attention on the biological effects of UV light. One obvious target for UVB-induced damage is DNA. Although a11 biological tissues are rich in UV-absorbing agents (largely nucleic acids and proteins) and plants produce additional UV-absorbin...